Over the past decade, research has revealed biomolecular condensates' relevance in diverse cellular functions. Through a phase separation process, they concentrate macromolecules in subcompartments shaping the cellular organization and physiology. In the nucleus, biomolecular condensates assemble relevant biomolecules that orchestrate gene expression. We here hypothesize that chromatin condensates can also modulate the nongenetic functions of the genome, including the nuclear mechanical properties. The importance of chromatin condensates is supported by the genetic evidence indicating that mutations in their members are causative (...) of a group of rare Mendelian diseases named chromatinopathies (CPs). Despite a broad spectrum of clinical features and the perturbations of the epigenetic machinery characterizing the CPs, recent findings highlighted negligible changes in gene expression. These data argue in favor of possible noncanonical functions of chromatin condensates in regulating the genome's spatial organization and, consequently, the nuclear mechanics. In this review, we discuss how condensates may impact nuclear mechanical properties, thus affecting the cellular response to mechanical cues and, eventually, cell fate and identity.Chromatin condensates organize macromolecules in the nucleus orchestrating the transcription regulation and mutations in their members are responsible for rare diseases named chromatinopathies. We argue that chromatin condensates, in concert with the nuclear lamina, may also govern the nuclear mechanical properties affecting the cellular response to external cues. (shrink)

Artificial intelligence (AI) and machine learning (ML) are increasingly integrated into the functioning of physical and digital products, creating unprecedented opportunities for interaction and functionality. However, there is a challenge for designers to ideate within this creative landscape, balancing the possibilities of technology with human interactional concerns. We investigate techniques for exploring and reflecting on the interactional affordances, the unique relational possibilities, and the wider social implications of AI systems. We introduced into an interaction design course (_n_ = 100) nine (...) ‘AI exercises’ that draw on more than human design, responsible AI, and speculative enactment to create experiential engagements around AI interaction design. We find that exercises around metaphors and enactments make questions of training and learning, privacy and consent, autonomy and agency more tangible, and thereby help students be more reflective and responsible on how to design with AI and its complex properties in both their design process and outcomes. (shrink)

How are abstract concepts and musical themes recognized on the basis of some previous experience? It is interesting to compare the different behaviors of human and of artificial intelligences with respect to this problem. Generally, a human mind that abstracts a concept (say, table) from a given set of known examples creates a table-Gestalt: a kind of vague and out of focus image that does not fully correspond to a particular table with well determined features. A similar situation arises in (...) the case of musical themes. Can the construction of a gestaltic pattern, which is so natural for human minds, be taught to an intelligent machine? This problem can be successfully discussed in the framework of a quantum approach to pattern recognition and to machine learning. The basic idea is replacing classical data sets with quantum data sets, where either objects or musical themes can be formally represented as pieces of quantum information, involving the uncertainties and the ambiguities that characterize the quantum world. In this framework, the intuitive concept of Gestalt can be simulated by the mathematical concept of positive centroid of a given quantum data set. Accordingly, the crucial problem “how can we classify a new object or a new musical theme (we have listened to) on the basis of a previous experience?” can be dealt with in terms of some special quantum similarity-relations. Although recognition procedures are different for human and for artificial intelligences, there is a common method of “facing the problems” that seems to work in both cases. (shrink)

The development of bacterial resistance to antibiotics is one of the best documented examples of contemporary biological evolution. Variability in the mechanisms of resistance depends on the diversity of genotypes in the huge bacterial populations, and also on the diversity of selective pressures that are produced along the antibiotic concentration gradients formed in the highly compartmentalized human body during therapy. These antibiotic gradients can be conceived as comprising selective compartments, each one of them defined as the concentration able to select (...) a particular genetic variant. In vitro experimental models confirm that some antibiotic resistant variants are selected only at certain selective concentrations of antibiotics. The correspondence between selective compartments and selectable variants could offer a way of describing more accurately the antibiotic selective landscapes and for taking measures to prevent the development of a major threat to the future of modern medicine. (shrink)

The development of bacterial resistance to antibiotics is one of the best documented examples of contemporary biological evolution. Variability in the mechanisms of resistance depends on the diversity of genotypes in the huge bacterial populations, and also on the diversity of selective pressures that are produced along the antibiotic concentration gradients formed in the highly compartmentalized human body during therapy. These antibiotic gradients can be conceived as comprising selective compartments, each one of them defined as the concentration able to select (...) a particular genetic variant. In vitro experimental models confirm that some antibiotic resistant variants are selected only at certain selective concentrations of antibiotics. The correspondence between selective compartments and selectable variants could offer a way of describing more accurately the antibiotic selective landscapes and for taking measures to prevent the development of a major threat to the future of modern medicine. (shrink)

The placenta’s role as a mediating passage between bodies has been a conceptual resource for feminist theorists and philosophers interested in developing more nuanced explanations of the maternal–fetal relation, a relation that has tended to be identified with maternal and fetal bodies rather than with the placenta between them. I draw on efforts by philosopher Luce Irigaray and her readers to theorise placental relations as a model for the negotiation of differences. In her more recent work, Irigaray figures the (...) placenta as an enveloping space of metaphorical enclosure. The placental relation in Irigaray’s work thus offers insights into the temporal structure of her theory of becoming and can inform a more ‘materialist’ account of pregnancy. I then consider how placental relations are conceptual resources for re-imagining relations of self–other in pregnancy, and for addressing emergent ethical concerns over the transformation of the placenta into a scientific object. (shrink)

The Empire strikes again. This article puts forward a sharp critique of Hardt and Negri’s Empire. Despite the book’s « post-modern » apparel, what it actually proposes is a pairing of two teleological « grand narratives». The first of these is a history of western political thought which is basically an apologia for the American constitution, whose ultimate manifestation is this hypothetical empire, the contemporary guise of an elusive political power. As for the second narrative, it sketches a history (...) of capitalism which, by way of its incarnations in the figures of the « professional worker » and the « mass worker », at last arrives at the figures of the « social worker » and the multitude, the latter being the-equally elusive- figure in a rather curious version of French communism. Faced with an epoch marked by a series of transformations requiring the most rigorous examination, telling such « stories » is a futile exercise. (shrink)

This article draws on the perspectives opened up by two recent collective volumes, one dedicated to the Tabula Aurea and the Concordantiae textuum discordantium [...] Thomae Aquinatis produced in the 15th century by Peter of Bergamo, and completed by his confrere Ambrose ‘de Alemania’ (Mario Meliado / Silvia Negri [Hrsg.], Widerspruche und Konkordanz. Peter von Bergamo und der Thomismus im Spatmittelalter), and the other focusing the tradition of the Summistae, i.e. the Renaissance and modern commentators on the Summa theologiae (...) of Thomas Aquinas (Lidia Lanza and Marco Toste [eds], ‘Summistae’. The Commentary Tradition on Thomas Aquinas’ ‘Summa Theologiae’ from the 15th to the 17th Centuries). On this basis, I propose to examine the way in which certain genres and specific types of theological and philosophical writings can mark an often decisive shift in the content and orientation of a particular tradition of thought (in this case, the Thomist tradition). (shrink)

Negli anni di passaggio dal XII al XIII secolo, il cisterciense Garnerio di Rochefort si dedica alla composizione di un breve trattato, il _De contrarietatibus in Sacra Scriptura_. L’opera, tuttora inedita, fa ricorso all’uso delle arti sermocinali per risolvere le ambiguità scritturali. Nel prologo del _De contrarietatibus_ emerge un peculiare interesse del cisterciense verso la disciplina della retorica e, in particolare, verso l’impiego delle figure tropiche nella comprensione dei contenuti della Rivelazione. A ben vedere, tuttavia, la scelta garneriana di ricorrere (...) all’affinamento degli strumenti della retorica per illuminare il significato della Scrittura trova una piena giustificazione solo alla luce della sua concezione della _natura_ e della _Scriptura_ come teofanie e/o simboli. Ora in quest’orizzonte simbolico, di impianto neoplatonico-dionisiano, è sempre all’opera nelle _res_, così come nel linguaggio, un meccanismo di traslazione, un’estensione della parola, oltre il suo contenuto ordinario, a un significato altro, di natura spirituale. Dunque la fattura retorica delle espressioni bibliche assume un valore conoscitivo, e non semplicemente ornamentale, perché capace di palesare, attraverso un dialettico gioco di corrispondenze e/o di rotture, una proporzionalità analogica tra il visibile e l’invisibile. _In the intervening years between the XII and XIII centuries, Cistercian Garnerius of Rochefort devoted himself to the composition of a short treatise,_ De contrarietatibus in Sacra Scriptura._ The work, still unpublished, makes use of the sermocinal arts to resolve scriptural ambiguities. The prologue to _De contrarietatibus _reveals a peculiar interest of the Cistercian in the discipline of rhetoric and, in particular, in the use of tropes in understanding the contents of Revelation. On closer inspection, however, garnerian’s choice to resort to the refinement of the tools of rhetoric to illuminate the meaning of Scripture finds full justification only in light of his conception of_ natura _and_ Scriptura_ as theophanies and/or symbols. Now in this symbolic horizon, of Neo-Platonic-Dionysian framework, there is always at work in _res_, as well as in language, a mechanism of translation, an extension of the word, beyond its ordinary content, to another meaning of a spiritual nature. So the rhetorical workmanship of biblical expressions assumes a cognitive, and not merely ornamental, value because it is capable of manifesting, through a dialectical interplay of correspondences and/or ruptures, an analogical proportionality between the visible and the invisible. _. (shrink)

The feminist critical deconstruction of Western culture and theology written by Luce Irigaray could be said to represent a certain branch of ecofeminist perspectives on religion. The article analyses the symbolic structures of suppression of women, body and nature and the exaltation of spirit, culture and the androcentric God, inherent in four hymns included in the new supplement to the book of hymns in the Lutheran Church of Sweden. The analysis shows that these symbolic structures are visible also in (...) these more recent hymns, even though they can be said to also consider and bring out women's experiences. Despite their `feminist' approach, they have not, on any deeper level, affected the subordination of women and the nature-given. (shrink)

En los últimos años, la relación entre la filosofía de la Ilustración y el cinismo ha logrado atraer la atención de los especialistas. En ese marco, los críticos suelen identificar las filosofías de Diógenes y Diderot. El objetivo del presente trabajo es revisar el vínculo que existe entre ambos con el fin de demostrar que el mismo es problemático y que, por esa razón, desborda las interpretaciones que se han presentado hasta el momento. Esto, por otra parte, arrojará luces sobre (...) la relación entre el materialismo de Diderot y su teoría ético-política. In recent years the relationship between the philosophy of the Enlightenment and cynicism has managed to attract the attention of scholars. In this framework, critics often identify Diogenes and Diderot's philosophy. The aim of this paper is to examine the relationship between Diderot and Diogenes in order to demonstrate that it is a problematic relationship that goes beyond the interpretations that have been presented so far. This, on the other hand, will shed light on the relationship between Diderot's materialism and his ethical and political theory. (shrink)

L’introduzione al fascicolo Analogia e medioevo sive vent’anni di analogie presenta il numero 18 di "Doctor Virtualis" e traccia le tappe fondamentali della rivista. Si delineano dapprima alcune linee della storia della rivista e le sue ispirazioni teoriche e storiografiche principali, per poi mettere in luce le ragioni della rilevanza del tema dell’analogia, come oggetto utilizzato e pensato nei secoli medievali e come strumento di ricerca storiografica, e infine si conclude con l’articolazione del fascicolo. The introduction to the issue (...) Analogy and the Middle Ages sive twenty years of analogies presents issue n. 18 of Doctor Virtualis and traces the milestones of the journal. It first sketches some lines of the history of the journal and its main theoretical and historiographical inspirations, then highlights the reasons for the relevance of the theme of analogy, as an object used and thought of in the medieval centuries and as a tool for historiographical research, and finally concludes with the articulation of the issue. (shrink)

I quattro Studi qui raccolti trattano alcuni temi significativi della filosofia settecentesca: il rapporto anima-corpo in Swedenborg, la presenza o meno di un livello di ragione nell' Homme naturel di Rousseau, la convergenza o meno di radicalismo politico e dimensione religiosa in Mably e in Morelly, la fondazione della scienza economica in Genovesi. Sono saggi molto diversi che sottendono interessi differenziati e stili di pensiero non collimanti; essi, tuttavia, sono accomunati da un'ottica squisitamente storiografica, che, pur nella consapevolezza di una (...) tensione tra presente e passato, tende a cogliere l'autonomia di quest'ultimo, la sua resistenza ad ogni schematizzazione, il suo sfuggire ad ogni tentativo di irrigidimento in immagini definitive. Il quadro del Settecento che emerge da questo volume da un lato mette in luce le diverse articolazioni che la filosofia settecentesca assume nei diversi contesti "nazionali" europei, dall'altro ne sottolinea slanci ma anche ambiguità e incoerenze, confermando quella grande complessità culturale dell' "età dei lumi" delineata dalla storiografia più recente. (shrink)

El conocimiento histórico –entendido como un proceso metacognitivo de asimilación constructiva sobre el pasado para explicar fenómenos– comporta un análisis del impacto y la transcendencia de determinados acontecimientos y procesos históricos, en cuya comprensión y valoración influye el concepto de relevancia histórica. Desde esta perspectiva es necesario implementar propuestas de evaluación sólidas, vinculadas al desarrollo competencial. El objetivo de este estudio es diseñar una guía de caracterización de los instrumentos evaluativos –actividades y ejercicios– más utilizados por el profesorado de Historia, (...) con el fin de optimizar los procesos de evaluación de esta competencia mediante una serie de descriptores estructurales, competenciales y transferenciales. Estos indicadores de pertinencia pueden marcar el camino de aquellos docentes que deseen perfeccionar su manera de evaluar lo históricamente determinante. En conclusión, este innovador planteamiento supone un proceso de formación continua del profesorado que contribuye a la mejora de la calidad educativa. (shrink)

Fidias López Valenzuela, Geógrafo de Profesión, al igual que muchos otros colegas en el desarrollo laboral, nos vemos enfrentados al concepto de Barrio. Innumerables han sido los intentos por llegar a un consenso sobre su definición, incluso visto por distintos profesionales como Arquitectos, Paisajistas y Geógrafos, entre otros; pero sin duda, a través de este Libro “Encantador era mi Barrio” se logra la esencia de lo que significa la palabra Barrio.El autor realiza una detallada descripción..

Mythical stories are, according to Luce Irigaray, one source where the matrix of repression, desire and correction of the female body is made visible. The Book of Revelation is one of the parts of the Bible told in a typical mythical language framework. It is also one of the most infamous biblical books because of its misogynist approach and repeated use of female stereotypes such as the whore and the pure bride. The purpose of this article is not to (...) deny the validity of this feminist critique, but to open up the meaning of the story of Revelation from an Irigarayan perspective as also to include possibilities of a counter-story where phallocentrism is challenged and finally altered into a new era where women, as well as other previously objectified categories, are aware of themselves as subjects in their own right. (shrink)

Reasoning es una obra monumental de más de mil páginas editada en estrecha colaboración por el filósofo Jonathan E. Adler y el psicólogo Lance J. Rips para esclarecer el intrincado campo de investigación relacionado con los fundamentos de la inferencia y, en general, del razonamiento humano. En la actualidad, en pocos casos va unido el trabajo de compilar y editar textos científicos con el afán enciclopédico: un proyecto editorial que sobrepasa con razón los objetivos de la mayor parte de los (...) libros editados para la recopilación de artículos en torno a un mismo tema de investigación. Reasoning supone un empeño de características enciclopédicas: ha conseguido convertirse en una referencia obligada desde que saliera a la luz en 2008 para ofrecer al lector especialista artículos científicos de las más reputadas y consolidadas voces en aquellos campos de conocimiento presentes ya en los proyectos enciclopédicos europeos del siglo de las luces, a saber: el significado del racionalismo, los límites imputables a la naturaleza del conocimiento humano, las paradojas presentes en la inducción, etc. (shrink)

Le langage égocentré et son dépassement par la parole. Une étude de l’acquisition du langage inspirée de Merleau-PontyDans les notes de travail du Visible et l’invisible, Merleau-Ponty se proposait d’élucider la nature du dépassement de l’être pré-langagier par la parole. Dans ses cours de la Sorbonne, il avait en outre jeté les fondements théoriques d’une confrontation fructueuse entre la linguistique et la psychologie de l’enfant, en ouvrant un dialogue de fond avec la théorie linguistique et avec les recherches psychologiques de (...) son époque sur l’acquisition du langage. Le phénomène de l’acquisition du langage par l’enfant nous fait assister à la transition de l’être pré-langagier à l’être parlant ; nous y trouvons l’occasion d’une mise en relation de l’incarnation perceptive et charnelle avec le corps parlant qui agit dans le champ symbolique.Cette étude reprend le projet de Merleau-Ponty, en s’appuyant sur les résultats récents de la recherche en matière de développement psycho-linguistique afin de mettre à l’épreuve les thèses merleau-pontiennes sur le langage. L’analyse herméneutique et phénoménologique de trois moments clés de l’acquisition du langage – indication, premiers mots, babil – met en lumière la nature du symbolisme, la fonction interpersonnelle de l’acte de parole et la nature de la grammaire en tant qu’événement diacritique existentiel.Linguaggio egocentrico e oltrepassamento nella parola. Uno studio dell’acquisizione del linguaggio ispirato a Merleau-PontyNelle note di lavoro de Il visibile e l’invisibile Merleau-Ponty si propone di chiarire la rivoluzione che il linguaggio introduce nell’essere pre-linguistico. Valendosi della propria familiarità con la teoria linguistica e con la coeva ricerca psicologica sull’acquisizione del linguaggio da parte dei bambini, nelle sue lezioni alla Sorbonne Merleau-Ponty ha gettato le fondamenta per un fruttuoso dialogo tra la linguistica e la psicologia infantile. Nel fenomeno dell’acquisizione linguistica del bambino assistiamo alla transizione dal pre-linguistico all’essere parlante: ciò fornisce un punto di vista privilegiato sulla connessione tra la percezione, l’incarnazione ed il corpo linguistico che agisce nell’ambito simbolico. Questo contributo riprende il progetto teorico merleaupontiano e guarda alle recenti scoperte nel campo dello sviluppo psico-linguistico per mettere alla prova le tesi di Merleau-Ponty sul linguaggio. Un’analisi ermeneutico-fenomenologicadei tre momenti dell’acquisizione del linguaggio – l’indicazione gestuale, le prime parole, i monologhi infantili nella culla prima di addormentarsi – permette di far luce sulla natura del simbolismo, sulla funzione interpersonale dell’atto linguistico e sulla natura della grammatica come evento esistenziale diacritico. (shrink)

Le langage égocentré et son dépassement par la parole. Une étude de l’acquisition du langage inspirée de Merleau-PontyDans les notes de travail du Visible et l’invisible, Merleau-Ponty se proposait d’élucider la nature du dépassement de l’être pré-langagier par la parole. Dans ses cours de la Sorbonne, il avait en outre jeté les fondements théoriques d’une confrontation fructueuse entre la linguistique et la psychologie de l’enfant, en ouvrant un dialogue de fond avec la théorie linguistique et avec les recherches psychologiques de (...) son époque sur l’acquisition du langage. Le phénomène de l’acquisition du langage par l’enfant nous fait assister à la transition de l’être pré-langagier à l’être parlant ; nous y trouvons l’occasion d’une mise en relation de l’incarnation perceptive et charnelle avec le corps parlant qui agit dans le champ symbolique.Cette étude reprend le projet de Merleau-Ponty, en s’appuyant sur les résultats récents de la recherche en matière de développement psycho-linguistique afin de mettre à l’épreuve les thèses merleau-pontiennes sur le langage. L’analyse herméneutique et phénoménologique de trois moments clés de l’acquisition du langage – indication, premiers mots, babil – met en lumière la nature du symbolisme, la fonction interpersonnelle de l’acte de parole et la nature de la grammaire en tant qu’événement diacritique existentiel.Linguaggio egocentrico e oltrepassamento nella parola. Uno studio dell’acquisizione del linguaggio ispirato a Merleau-PontyNelle note di lavoro de Il visibile e l’invisibile Merleau-Ponty si propone di chiarire la rivoluzione che il linguaggio introduce nell’essere pre-linguistico. Valendosi della propria familiarità con la teoria linguistica e con la coeva ricerca psicologica sull’acquisizione del linguaggio da parte dei bambini, nelle sue lezioni alla Sorbonne Merleau-Ponty ha gettato le fondamenta per un fruttuoso dialogo tra la linguistica e la psicologia infantile. Nel fenomeno dell’acquisizione linguistica del bambino assistiamo alla transizione dal pre-linguistico all’essere parlante: ciò fornisce un punto di vista privilegiato sulla connessione tra la percezione, l’incarnazione ed il corpo linguistico che agisce nell’ambito simbolico. Questo contributo riprende il progetto teorico merleaupontiano e guarda alle recenti scoperte nel campo dello sviluppo psico-linguistico per mettere alla prova le tesi di Merleau-Ponty sul linguaggio. Un’analisi ermeneutico-fenomenologicadei tre momenti dell’acquisizione del linguaggio – l’indicazione gestuale, le prime parole, i monologhi infantili nella culla prima di addormentarsi – permette di far luce sulla natura del simbolismo, sulla funzione interpersonale dell’atto linguistico e sulla natura della grammatica come evento esistenziale diacritico. (shrink)

El propósito del artículo es explicar el genocidio de la Unión Patriótica en clave de la economía nacional y su ubicación estratégica a partir de una aproximación teórica desde algunos elementos propuestos por Antonio Negri y Michael Hardt. Como conclusión se destaca que el genocidio de la up fue consecuencia de su poderío local, que ponía en riesgo la continuidad de las clases políticas dominantes en razón de sus propuestas como colectivo político. Así mismo, este hecho produjo que a (...) raíz de su origen se construyera sobre ellos un relato negativo de enemigos de la sociedad civil. Por último, las propuestas de memoria que se identificaron son consecuencia de la conquista y de la lucha social por parte de las víctimas. (shrink)

Les travaux de Margareth Rago, historienne assez connue du public brésilien, portent sur l’histoire des femmes et des rapports entre les genres, dans une perspective marquée par les travaux de Michel Foucault. Dans ce livre, l’auteure utilise ce cadre théorique pour analyser la vie et l’œuvre de Luce Fabbri, intellectuelle anarchiste, sans cacher une certaine sympathie pour son sujet. Sur un ton alerte, l’ouvrage raconte la vie de cette femme-écrivain italienne qui a vécu 92 ans. Le savant mé...

Nella tradizione agostiniana del XII secolo compaiono temi e linguaggi che suggeriscono la presenza, accanto al discorso teologico, di un discorso dell'uomo sull'uomo. Si analizza la figura di Maria Maddalena in alcuni autori del XII secolo e l'allegoria nuziale nei Sermones super Cantica di Bernardo di Clairvaux. La lettura viene condotta sulla base di categorie concettuali di carattere psicoanalitico, in quanto tali categorie trovano la propria origine, prima ancora che nel pensiero, nella più concreta e profonda esperienza umana. Ed (...) è proprio il collocarsi all'interno di questa viva esperienza umana che consente di cogliere in modo più diretto la dimensione antropologica che pare emergere dagli scrittori monastici di questo periodo. (shrink)

Spanish translation of Field, S. L. (2012). 'Democracy and the multitude: Spinoza against Negri'. Theoria: A Journal of Social and Political Theory, 59(131), 21-40. Translated by María Cecilia Padilla and Gonzalo Ricci Cernadas. Negri celebra una concepción de la democracia en la que los poderes concretos de los individuos humanos no se alienan sino que se agregan: una democracia de la multitud. Pero ¿cómo puede actuar la multitud sin alienar el poder de nadie? Para contestar esta dificultad, (...) class='Hi'>Negri explícitamente apela a Spinoza. Sin embargo, en este trabajo, sostengo que la filosofía de Spinoza no respalda el proyecto de Negri. Por el contrario, argumento que la multitud spinozista evita la jerarquía interna por medio de la mediación de las instituciones políticas y no a pesar de ellas; de la misma manera, estas instituciones tampoco simplemente emanan de la multitud tal cual es, sino que estructuran, contienen y canalizan sus pasiones. En particular, las instituciones requeridas no son las de la democracia simple y directa. Puede ser que existan otros argumentos no spinozistas en los cuales Negri pueda basar su teoría, pero no puede defender legítimamente su concepción de la multitud democrática apelando a Spinoza. (shrink)

Antonio Negri wrote the two essays that comprise Time for Revolution while serving a prison sentence for alleged involvement with radical left-wing groups. Although the essays were written two decades apart, their concerns are the same: is there a place for resistance in a society utterly subsumed by capitalism? In the wake of the global crisis of capitalism heralded by the 2008 crash, the question has never been more relevant and Negri remains an insightful and passionate guide to (...) any attempt to answer it. (shrink)

Razón, poesía, historia.--La cuestión del estoicismo español.--El querer.

Dibujar el pensamiento de Seneca es dibujar su figura viva, trazar el esquema de su persona. Seneca es un mediador que para alzarse sobre nosotros necesita de nuestra necesidad, pues solo apoyado en nuestra indigencia tiene sentido. Maria Zambrano lleva a cabo un lucido estudio de la figura y significacion del pensador cordobes y presenta una seleccion de sus escritos.

A sequent calculus is given in which the management of weakening and contraction is organized as in natural deduction. The latter has no explicit weakening or contraction, but vacuous and multiple discharges in rules that discharge assumptions. A comparison to natural deduction is given through translation of derivations between the two systems. It is proved that if a cut formula is never principal in a derivation leading to the right premiss of cut, it is a subformula of the conclusion. Therefore (...) it is sufficient to eliminate those cuts that correspond to detour and permutation conversions in natural deduction. (shrink)

Luce Irigaray is widely recognised as one of the leading figures in the study of women, language and culture. She is arguably the most original and provocative feminist theorist in contemporary French thought. Over recent years her ideas have become massively influential, not least in feminist literary theory, where they have opened up possibilities for reading women's writing and theorizing language. In _Je, Tu, Nous_ Luce Irigaray offers the clearest introduction available to her own work. In a series (...) of brief and direct pieces on gender, language, power and patriarchal mythologies, she lays out what for her is the central problem for women in the modern world. The essays span Irigaray's thought on the importance of difference in culture, in a style that is remarkably informal, open and engaging. This is a remarkable book which will introduce Irigaray's philosophy, with her vision of necessary cultural change, to the widest audience so far. (shrink)

In eleven acute and widely ranging essays, Irigaray reconsiders the question of female sexuality in a variety of contexts that are relevant to current discussion of feminist theory and practice.

Spectroscopy is a scientific topic at the interface between Chemistry and Physics, which is taught at high school level in relation with its fundamental applications in Analytical Chemistry. In the first part of the paper, the topic of spectroscopy is analyzed having in mind the well-known Johnstone’s triangle of chemistry education, putting in evidence the way spectroscopy is usually taught at the three levels of chemical knowledge: macroscopic/phenomenological, sub-microscopic/molecular and symbolic ones. Among these three levels, following Johnstone’s recommendations the macroscopic (...) one is the most useful for high school students who learn spectroscopy for the first time. Starting from these premises, in the second part of the paper, we propose a didactic sequence which is inspired by the historical evolution of spectroscopic instruments from the first spectroscopes invented by Gustav Kirchhoff and Robert Bunsen in 1860 to the UV–vis spectrophotometers which became common since the 1960s. The idea behind our research is to analyze the conceptual advancements through the history of spectroscopy and to identify the key episodes/experiments and spectroscopic instruments. For each of them, a didactic activity, typically an experiment, is then proposed underlining the relevant aspects from the chemistry education point of view. The present paper is the occasion to reflect on the potentialities of an historical approach combined with a laboratorial one, and to discuss the role of historical instruments and related technological improvements to teach spectroscopy. (shrink)

A radically subversive critique brings to the fore the masculine ideology implicit in psychoanalytic theory and in Western discourse in general: woman is defined as a disadvantaged man, a male construct with no status of her own.

Hilary Putnam is one of the world’s leading philosophers. His highly original and often provocative ideas have set the agenda for a variety of debates in philosophy of science, philosophy of mind and philosophy of language. His now famous philosophical thought experiments, such as the ‘Twin earth’ and ‘the brains in the vat’ have become part of the established canon in philosophy and cognitive science. _Reading Putnam_ is an outstanding overview and assessment of Hilary Putnam’s work by a team of (...) international contributors, and includes replies by Putnam himself. Divided into clear sections, it contains chapters on key aspects of Putnam’s large body of writing, including: Scientific realism and the changes that Putnam’s thought has undergone on this topic analyticity and ontology, including the important interconnections between the views of Putnam and Quine Putnam’s arguments concerning externalist views of meaning and reference, questions of conceptual relativity, and his preoccupation with ethics through a denial of the fact–value dichotomy Putnam’s developing views on perception. Offering an excellent survey of Putnam’s work, _Reading Putnam_ is essential for those studying philosophy of mind, philosophy of language, and philosophy of science, as well as for anyone interested in contemporary philosophy. (shrink)

In the literature, the pragmatic dimension of metaphors has been clearly acknowledged. Metaphors are regarded as having different possible uses, especially pursuing persuasion. However, an analysis of the specific conversational purposes that they can be aimed at achieving in a dialogue and their adequacy thereto is still missing. In this chapter, we will address this issue focusing on the classical distinction between the explanatory and persuasive uses of metaphors, which is, however, complex to draw at an analytical level and often (...) blurred and controversial also from a theoretical point of view. Building on the analysis of explanation in different theories and fields of study, we show how it can be conceived as characterized by a cognitive and a pragmatic dimension, where the transference of understanding is used pragmatically for different dialogical goals - such as informing, making a joint decision, and most importantly persuading. In this sense, the cognitive effects of understanding are not incompatible with a persuasive dialogical purpose. This theoretical proposal will be applied to examples drawn from the medical context, to show how a pragmatic approach to explanation can account for the complexity of the cases that can be found in actual dialogical contexts. (shrink)